ea0020p597 | Neuroendocrinology, Pituitary and Behaviour | ECE2009
Kelestimur Haluk
, Yilmaz Bayram
, Ayar Ahmet
, Kilic Ertugrul
, Ozcan Mete
, Kilic Ulkan
, Alcin Ergul
Chronic central administration of KiSS-1 peptide to immature female rats induces pubertal maturation, characterized by advanced vaginal opening, increased uterine and ovarian weights, elevated levels of luteinizing hormone (LH) and estrogen. There is evidence that the pineal gland may be also involved in puberty onset because melatonin secretion declines near puberty. We have investigated whether there is an interaction between kisspeptin and melatonin in timing of puberty ons...